Strategic Fluorination to Achieve a Potent, Selective, Metabolically Stable, and Orally Bioavailable Inhibitor of CSNK2.

Although no statistically significant difference in phosphorylation of Ser2 of EIF2S2 was observed, there was a small decrease at the 3 h time point that did not reach statistical significance ( p = 0.14) ( Figure 6 C).

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