Lentiviral vector packaging and producer cell lines yield titers equivalent to the industry-standard four-plasmid process.

In summary, over 30 passages a negative trend in LVV titer was observed: with 2 rounds of cryopreservation and 3 rounds of revival, clones LVPr001_3.5 and LVPr001_4.3 lost 3.4- to 4.7-fold productivity.

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