Schwann cell-derived exosomes ameliorate peripheral neuropathy induced by ablation of dicer in Schwann cells.

Eight weeks after TAM, PLP-cKO mice started to show impairments of motor coordination (Beam Walk test), thermal sensitivity (Plantar test), and sciatic nerve MCV and SCV, but the impairments did not reach statistical significance compared to WT mice, except for MCV ( Figure 2 ).

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