RLS-0071, a novel anti-inflammatory agent, significantly reduced inflammatory biomarkers in a randomised human evaluation of mechanisms and safety study.

IL-8 showed a trend of a one-half log decrease at 6 h for the low-dose arm compared with placebo (mean difference: −0.536; p=0.062) ( figure 4b ).

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These results were persistent with a trend towards significance in the natural log-transformed sputum percentages of neutrophils at 24 h post LPS and demonstrate a consistent pattern.

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