The Abl1 tyrosine kinase is a key player in doxorubicin-induced cardiomyopathy and its p53/p73 cell death mediated signaling differs in atrial and ventricular cardiomyocytes.

J Transl Med · 2024 · PMC11403941 · PMID 39285385

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did not reach statistical significanceno p-value reported

Consistent with an earlier report [ 178 ], the SERCA2 Ca 2+ ATPase expression was slightly repressed but did not reach statistical significance.

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highly significantno p-value reported

Extraordinarily, Abl1 signaling differed in the heart with highly significant regulations of Abl1, p53 and p73 in atrial cardiomyocytes.

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