Sex-specific molecular signature of mouse podocytes in homeostasis and in response to pharmacological challenge with rapamycin.

Phosphorylation of AMPK as indicator for the general energy status revealed a tendency towards higher levels in female compared to male, yet due to high interindividual variability especially in the female group this difference did not reach statistical significance (p-value = 0.07, Supplementary Figure S7).

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a Univariate linear regression analysis indicated a highly significant positive correlation of log2FC of male versus female commonly described genes of podocytes of this study and young cells of renin lineage (Wang Y et al., Aging (Albany NY). 2018; https://doi.org/10.18632/aging.101416).

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