Barely Significant
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Quantitative analysis of nortriptyline's analgesic properties: a comparative systematic review and meta-analysis.

BMJ Open · 2024 · PMC11404244 · PMID 39122393

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hedged sentence
0.0600
closest p · 1.2× alpha
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boldest claim

The sentences

did not reach statistical significancep=0.06so close (0.05 < p ≤ 0.1)
41 It was also reported that while nortriptyline is beneficial in reducing knee osteoarthritis pain, it is not superior to placebo since their difference did not reach statistical significance (p=0.06). 34 Furthermore, some studies compared nortriptyline’s efficacy with other analgesics; it was reported that nortriptyline can be as efficacious as amitriptyline in controlling peripheral neuropathic pain 42 and postherpetic neuralgia (PHN). 35 While one study reports that nortriptyline was

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