It is worth noting that in the process of disease progression from the nonfrail stage to the frail stage, IL-17 showed a gradual increase, whereas IFN-γ showed a trend of first decreasing and then increasing, and IGF-1 showed a trend of first increasing and then decreasing, which is worthy of further exploration ( Table 4 ).
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Prebiotics improve frailty status in community-dwelling older individuals in a double-blind, randomized, controlled trial.
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