Human papillomavirus 16 replication converts SAMHD1 into a homologous recombination factor and promotes its recruitment to replicating viral DNA.

Endothall statistically increased the recruitment of E2 to the viral genome in UMSCC104 (right-hand panel) and increased SAMHD1 recruitment, although it marginally failed to reach statistical significance (left-had panel, P value = 0.0505).

also in 6,035 other papers

E6 DNA levels were measured, and the strikingly consistent result is that, in the presence of SAMHD1 T592D, there is a highly significant reduction in genome copy number to almost undetectable levels.

also in 132,142 other papers