Association of direct oral anticoagulants and warfarin with incidence of dementia in atrial fibrillation patients: A systematic review and meta-analysis.

Although in the vascular dementia group, the incidence of dementia in the DOACs group was lower than that in the warfarin group (RR: 0.841; 95 % CI, 0.61–0.143), the difference did not reach statistical significance (Z = 1.11, P = 0.269), as displayed in Table 5 . 4 Sensitivity analyses and publication bias Sensitivity analyses were conducted by excluding the included studies one by one, and the combined effect sizes did not change significantly, indicating that the results of the meta-analysis were robust and reliable.

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