The pSer9GSK3β/GSK3β ratio was also increased by 1.5- and 1.7-fold in FXN1 and FXN2 cells, respectively, although the differences did not reach statistical significance ( Fig. 8 C and D).
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Deciphering the ferroptosis pathways in dorsal root ganglia of Friedreich ataxia models. The role of LKB1/AMPK, KEAP1, and GSK3β in the impairment of the NRF2 response.
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