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Necrotising enterocolitis suspicion in newborns with duct-dependent congenital heart disease: prognosis and risk factor.

BMJ Paediatr Open · 2024 · PMC11409277 · PMID 39284616

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20 In the study of Van Der Heide, comparing 16 CHD infants with NEC (Bell stages II and III) and selected 16 controls, difference in DBP did not reach statistical significance, but demonstrated the same direction towards (relative) hypoxia/ischaemia in NEC infants. 23 These data support the hypothesis according to which a drop in mesenteric perfusion pressure resulting from aortic diastolic steal or global hypotension leads to intestinal ischaemia and subsequent necrosis in newborns with duct-dependent CHD.

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