Barely Significant
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Effect of homocysteine-lowering nutrients on blood lipids: results from four randomised, placebo-controlled studies in healthy humans.

PLoS Med · 2005 · PMC1140947 · PMID 15916468

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The increases in LDL cholesterol concentrations in the groups that ingested 1.5 g/d of betaine and 3 g/d of betaine for 6 wk were higher than in the placebo group, but these changes did not reach statistical significance ( Figure 6 ).

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