<i>PITAR</i>, a DNA damage-inducible cancer/testis long noncoding RNA, inactivates p53 by binding and stabilizing <i>TRIM28</i> mRNA.

Elife · 2024 · PMC11415074 · PMID 39302097

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quite significantno p-value reported

In the cycloheximide experiment in Figure 5E, the half-life of p53 is increased by 60 % (50 mins to 120 mins), which is quite significant in altering the DNA damage response by p53.

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