Treatment of Painful Diabetic Neuropathy with 10 kHz Spinal Cord Stimulation: Long-Term Improvements in Hemoglobin A1c, Weight, and Sleep Accompany Pain Relief for People with Type 2 Diabetes.

After 24 months, study participants experienced a highly significant improvement in sleep quality, with the PSQ-3 score decreasing by a mean of 65.2%, corresponding to a mean value of 1.9 ± 0.2 cm ( P < 0.001).

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48 There is also some early evidence suggesting potential improvements to IENFD in DRG stimulation patients with painful polyneuropathy; however, the analysis did not reach statistical significance. 49 A small feasibility study of 10 kHz SCS in PDN has shown more promising results, demonstrating a significant increase in IENFD in both the proximal thigh and distal legs after 6 months of treatment. 27 Treatment results with 10 kHz SCS also appear more favorable than current pharmacological options for neuropathic pain.

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