The impact of large core and late treatment trials: An update on the modelled annual thrombectomy eligibility of UK stroke patients.

For instance, the MR CLEAN LATE trial showed a clear trend in a reducing Odds Ratio for benefit from thrombectomy in the later onset to randomisation subgroups, with only the earliest 5.8–9.8 h subgroup demonstrating a statistically significant benefit from thrombectomy on its own, even though the 3 temporal subgroups were similarly sized.

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