Associations between vitamin D status and biomarkers linked with inflammation in patients with asthma: a systematic review and meta-analysis of interventional and observational studies.

A sensitivity analysis that included the three studies with symmetrically distributed data confirmed the inverse association between 25(OH)D and IgE but failed to reach statistical significance (β (95% CI) = − 0.19 (–0.52 to 0.13); I 2 = 60%; P = 0.08; N = 3 studies) (Fig. 5 C).

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