Immune checkpoint pathways in glioblastoma: a diverse and evolving landscape.

Front Immunol · 2024 · PMC11427296 · PMID 39346924

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did not reach statistical significanceno p-value reported

In a preclinical GBM model, combinatorial therapy of PD1 and LAG-3 blockade showed increased survival over no treatment, but the survival benefit did not reach statistical significance when compared to that of either anti-PD1 or anti LAG-3 therapy alone ( 87 ).

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