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The Role of Adiponectin and Leptin in Fibro-Calcific Aortic Valve Disease: A Systematic Review and Meta-Analysis.

Biomedicines · 2024 · PMC11428218 · PMID 39335491

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Our results are in line with the latter, since this meta-analysis revealed a consistent relationship between elevated leptin levels and severe aortic stenosis, even if, in the early stages, this association did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.