Considerations for Using Neuroblastoma Cell Lines to Examine the Roles of Iron and Ferroptosis in Neurodegeneration.

However, the addition of supplemental iron only increased ferritin protein expression in undifferentiated SH-SY5Y cells ( Figure 1 E) whereas increased ferritin expression in hemin-treated Neuro-2a cells did not reach statistical significance ( Figure 1 F, p = 0.058).

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