Identifying and characterizing disease subpopulations that most benefit from polygenic risk scores.

The SZ_128 and SZ_342 features had no association, but the SZ_1M was higher in this subgroup compared to the other cases (Cohen’s d = 2.66) and could have approached significance (p-value = 1.48 × 10 −4 ) if not for the Bonferroni correction.

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Although this group had a higher BMI, the effect size was relatively small and did not achieve significance.

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