Platelet count has a nonlinear association with 30-day in-hospital mortality in ICU end-stage kidney disease patients: a multicenter retrospective cohort study.

Notably, the 30-day in-hospital mortality rate showed a decreasing trend from Q1 to Q3, but surprisingly, the mortality rate in Q4 rebounded, exceeding the level of Q3( P < 0.001).

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The log-likelihood ratio test comparing the piecewise model to a standard linear model was highly significant ( P < 0.001), signifying the superior fit of the piecewise model to the data.

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A significant trend in 30-day in-hospital mortality across platelet count quartiles was identified (P for trend = 0.0019).

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