A Case-Control Study Supports Genetic Contribution of the <i>PON</i> Gene Family in Obesity and Metabolic Dysfunction Associated Steatotic Liver Disease.

Highly significant results were consistently observed for rare and very rare PON2 variants when comparing samples without liver fibrosis to samples with varying stages of liver fibrosis.

also in 132,142 other papers

Remarkably, all nominally significant associations were observed in the PON1 gene, with at least one nominally significant result per testing group.

also in 7,732 other papers

Some borderline significant results were obtained for rare PON3 variants when comparing patients without inflammation or fibrosis to those with varying stages of these liver injury parameters.

also in 11,409 other papers