In immune treatment GEO dataset analysis, while IL7R high expression patients were more likely to respond to immunotherapy and possessed a longer survival times in melanoma, renal cell carcinomas and liver cancers, the difference in ORR did not reach statistical significance, we thought it may due to the small sample size and the influence of multi-line therapy.
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Comprehensive analysis to identify IL7R as a immunotherapy biomarker from pan-cancer analysis to in vitro validation.
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