Self-perceived quality of life, cognitive and behavioural impairment in amyotrophic lateral sclerosis.

For the interaction with people and the environment subdomain (see Table 4 ), while the Step 1 model explained 2.4% of the variance with no significant age, gender, and ALSFRS-R predictors, the Step 2 model showed the overall psychosis score as a significant negative predictor of this QoL subdomain ( β = − 0.32, p = 0.001), with the behaviour score trending towards significance ( β = − 0.18, p = 0.06).

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