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The Crisis of Macrolide Resistance in Pneumococci in Latin America.

Am J Trop Med Hyg · 2024 · PMC11448541 · PMID 39084209

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showed a trendno p-value reported
In the 1980s, surveillance studies showed a trend of increasing macrolide resistance worldwide.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.