Clinicogenomic predictors of outcomes in patients with hepatocellular carcinoma treated with immunotherapy.

Multivariable analysis confirmed the significant association of worse ECOG PS and Child-Pugh score with reduced 1st line and 2nd line PFS, while BCLC stage C disease compared to stage B was also associated with increased risk of progression in 2nd line but did not reach statistical significance ( Figure 2 , Supplementary Table S2 ).

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