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Evaluation of the beneficial effects of a GABA-based product containing <i>Melissa officinalis</i> on post-inflammatory irritable bowel syndrome: a preclinical study.

Front Pharmacol · 2024 · PMC11449869 · PMID 39372212

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In the curative protocol, DNBS + GABA-Mo rats showed a trend in reduction of LBP levels, but the other treatment groups were not significantly altered ( Figure 14B ). 4 Discussion Based on these preclinical results, it is possible to conclude that treatment with GABA- Melissa officinalis , especially in the curative protocol, can counteract the establishment and persistence of visceral hypersensitivity resulting from an inflammatory insult.

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