Stroke volume was decreased significantly only in Fxn -cKO males (-29%, from 34.3±4.6 μl in CTRL to 24.5±8.9 μl in KO, p < 0.05), while Fxn -cKO females only showed a trend towards a decline in stroke volume (-17%, NS) (Fig. 2g ).
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Sexual dimorphism in a mouse model of Friedreich's ataxia with severe cardiomyopathy.
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