Myopic shift in female mice after ovariectomy.

A longitudinal study from Singapore suggested that rather than pubertal changes, growth spurts and possible growth hormone surges may be significant mediators of myopia progression 38 .

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Male mice showed a propensity of a higher degree of myopia and a faster progression of axial elongation than female mice, these differences did not reach statistical significance (Fig. 1 a,b).

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