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Additional impact of genetic ancestry over race/ethnicity to prevalence of KRAS mutations and allele-specific subtypes in non-small cell lung cancer.

HGG Adv · 2024 · PMC11452329 · PMID 38902927

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Additionally, a numerically decreased trend for KRAS mutation (OR = 0.6, p = 0.18) and an increased trend for KRAS transition events (OR = 1.86, p = 0.23) were observed in SIRE-Asian patients compared to SIRE-White patients, although these trends did not reach statistical significance, likely due to the reduced sample size in the stratified analyses ( Table S9 ).

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