JNK Pathway-Associated Phosphatase Deficiency Facilitates Atherosclerotic Progression by Inducing T-Helper 1 and 17 Polarization and Inflammation in an ERK- and NF-κB Pathway-Dependent Manner.

Furthermore, in the serum, IFN-γ was increased ( P <0.05), and IL-17A showed an increasing tendency but did not reach statistical significance ( P =0.150), whereas IL-4 levels did not differ between JKAP fl/fl CD4 Cre mice and control mice ( Fig.6E ) .

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