Therapeutic effects of Kangxian Yanshen formula on patients with chronic kidney disease stages 3-4: a retrospective cohort study.

All showed an increasing trend at months 24 and 36, with the magnitude of change in the 24-hour proteinuria difference being most pronounced at month 24 (Kangxian Yanshen Formula group: Δ0.21 [± 0.92 SD] g/d versus Western medicine group: Δ0.41 [± 1.59 SD] g/d; between-group difference Δ−0.45 g/d; P = 0.021).

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Participants in both groups showed a decreasing trend in eGFR at months 24 and 36.

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Serum creatinine remained almost constant among participants in the Kangxian Yanshen Formula group, whereas participants in the Western medicine group showed a trend toward a significant increase in serum creatinine.

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