Therapeutic drug monitoring for valproate: deriving a novel formula for calculation of free concentration.

Eur J Clin Pharmacol · 2024 · PMC11458675 · PMID 39150536

Europe PMC DOI

hedged sentence

0.0669

closest p · 1.3× alpha

0.0669

boldest claim

The sentences

did not reach statistical significancep = 0.0669so close (0.05 < p ≤ 0.1)

A higher percentage of male participants (31.6%) presented with elevated free VPA concentration compared to females (14.0%), although this difference did not reach statistical significance ( p = 0.0669).

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