Depressive Symptoms in Multiple Sclerosis: Links to Body Composition, Physical Activity, and Functional Ability.

The individuals with MS and depression symptoms were more likely to have adiposity (%BF) compared to individuals without symptoms of depression (OR=1.07; 95% CI: 1.01–1.13; P =.026) and a higher fat mass (Me: 21.45 vs 18.30; P =.036), but in the latter case, the OR did not reach statistical significance (OR: 1.04;95% CI: 0.99–1.09; P =.065).

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In turn, the ‘vicious circle’ effect may be significant for reducing motor function, and thus increasing disability [ 28 ].

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