Polygenic scores for complex traits are associated with changes in concentration of circulating lipid species.

PLoS Biol · 2024 · PMC11460696 · PMID 39325819

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nominally significantP < 0.05actually significant

All the 678 PGS-lipid associations were at least nominally significant ( P < 0.05) in this sensitivity analysis with consistent direction of effects and similar effect sizes (R 2 = 0.94, P < 2.2 × 10 −16 ) ( S5 Table ).

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