Cryopreserved apoptotic mesenchymal stromal cells retain functional efficacy in suppressing an allergic inflammation in a murine model.

Furthermore, we also found that the levels of the T H 2 cytokines IL-4 and IL-5 in the bronchoalveolar lavage fluid were lower in mice treated with fresh and freeze-thawed ApoMSCs when compared to vehicle control, and whilst this did not reach statistical significance, the trend was consistent with the profile observed in pulmonary eosinophil recruitment ( Supplementary Figure S2 ).

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