While there was a trend toward lower cumulative bacterial burdens (chromosomal equivalents [CEQs]; an estimate of total live and dead bacilli) in granulomas from IgG NHPs, these differences did not reach statistical significance ( Figures 2 C and S2 B).
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CD4<sup>+</sup> T cells re-wire granuloma cellularity and regulatory networks to promote immunomodulation following Mtb reinfection.
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