Dysregulated C1q and CD47 in the aging monkey brain: association with myelin damage, microglia reactivity, and cognitive decline.

Front Immunol · 2024 · PMC11466761 · PMID 39399501

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hedged sentences

0.0586

closest p · 1.2× alpha

0.0809

boldest claim

The sentences

approached significancep =0.0586so close (0.05 < p ≤ 0.1)

The decreases in MBP levels were also associated with increasing cognitive impairment index (CII) score but only approached significance [F(1,28)= 3.888, R 2 = 0.1219, p =0.0586] ( Figure 2C ).

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approached significantp =0.0809so close (0.05 < p ≤ 0.1)

The decreased ratio of ramified:hypertrophic microglia correlated with higher CII score [F(1,30)= 10.34; R 2 = 0.2564, p =0.0031] ( Figure 4J ) and the increased density of Gal3+ cells approached significant correlation with CII score [F(1,30)=3.263, R 2 = 0.09810, p =0.0809] but density of C1q+ cells did not correlate with cognitive impairment [F(1,30)= 0.1048, R 2 = 0.003482, p =0.7484] (data not shown).

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