Recurrence pattern of glioblastoma treated with intensity-modulated radiation therapy versus three-dimensional conformal radiation therapy.

Radiat Oncol J · 2024 · PMC11467484 · PMID 39354825

Europe PMC DOI

hedged sentences

0.0790

closest p · 1.6× alpha

0.0790

boldest claim

The sentences

did not reach conventional levels of significancep = 0.079so close (0.05 < p ≤ 0.1)

Conversely, the study found a trend toward lower out-of-field recurrence with IMRT in patients who did not receive GTR (OR = 2.95; p = 0.079), although this did not reach conventional levels of significance (p = 0.079).

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marginal significancep = 0.079so close (0.05 < p ≤ 0.1)

In partial tumor removal or biopsy cases, out-of-field recurrence was less frequent in the IMRT (16.2%) than in the 3D-CRT (36.3%) group, with marginal significance (p = 0.079).

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near-significantno p-value reported

The near-significant p-value suggests that there is an approximately 195% increase in the odds of out-of-field recurrence with 3D-CRT compared with IMRT, which may be clinically relevant, indicating that IMRT could be a better option in cases where GTR is not achieved.

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