Enhancement of endogenous midbrain neurogenesis by microneurotrophin BNN-20 after neural progenitor grafting in a mouse model of nigral degeneration.

Before looking at the grafts, we assessed the progress of dopaminergic degeneration, focusing on the contralateral, non-grafted, hemispheres of control mice (that received vehicle) ( Figure 3D ) and we found that the numbers of TH + cells at P75 were almost 1/3 rd of those at P60, even though this decrease did not reach statistical significance.

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