An insight into pharmacokinetics and dose optimization of antimicrobials agents in elderly patients.

Front Pharmacol · 2024 · PMC11471682 · PMID 39403139

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hedged sentence

0.0778

closest p · 1.6× alpha

0.0778

boldest claim

The sentences

showed a trendp = 0.0778so close (0.05 < p ≤ 0.1)

Currently, only a PBPK study has demonstrated that CL of pyrazinamide correlated with creatinine clearance ( p = 0.0349) and showed a trend toward smaller CL values with advancing age ( p = 0.0778) ( Peloquin et al., 1997 ).

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