ADAR1 plays a protective role in proximal tubular cells under high glucose conditions by attenuating the PI3K/AKT/mTOR signaling pathway.

Open Med (Wars) · 2024 · PMC11472009 · PMID 39403253

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However, the application of 8-azaadenosine showed a trend opposite to that of ADAR1 overexpression ( Figure 2e and f ).

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