Barely Significant
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The global, regional, and national patterns of change in the burden of congenital birth defects, 1990-2021: an analysis of the global burden of disease study 2021 and forecast to 2040.

EClinicalMedicine · 2024 · PMC11474384 · PMID 39416384

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showed a trendno p-value reported
Except for low-SDI regions, all other regions generally showed a trend of an initially slowing and then accelerating decline.

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