We observed significant negative correlations between the increase in weight ( p = 0.043), FM ( p = 0.023), and FFM ( p = 0.033) measured by skinfolds and the baseline FEV1/FVC ratio, as well as positive correlations between the number of severe exacerbations in the year prior to starting ETI and the increase in FFM (BIA) ( p = 0.022) and almost significant FFM by skinfolds ( p = 0.08). 4.
Knott-Torcal et al., in 36 pwCF, also observed a significant increase in BMI after six months of treatment, as well as an increase in FM and visceral fat area, with a trend towards an increase in FFM (by approximately 600 g), though this did not reach statistical significance [ 17 ].
In our study, we observed significant decreases in faecal calprotectin levels, as well as nitrogen and fat in the stools, while LDL cholesterol and vitamin A levels increased significantly, with vitamin E, albumin, and total cholesterol levels nearing significance.