Efficacy and safety of traditional Chinese medicine in managing bone loss post-endocrine therapy in hormone receptor-positive breast cancer patients.

Although improvements in clinical efficacy did not reach statistical significance (relative risk [RR] = 1.122, 95% CI: 0.933–1.348), the studies indicated good safety of the treatment, with most studies reporting no significant adverse reactions.

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There was also a positive trend in enhancing femoral neck bone density (SMD = 0.645, 95% CI: 0.321–0.970).

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