First onsets of MDD had a similar pattern in male and female participants; although, this did not reach statistical significance in the male sample during the ‘perimenopause’ proxy (RR of 1.13 (95% CI 1.00–1.29); Extended Data Fig. 2 and Supplementary Table 3 ).
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Exploration of first onsets of mania, schizophrenia spectrum disorders and major depressive disorder in perimenopause.
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