Barely Significant
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SARS-CoV-2 ORF 3a-mediated currents are inhibited by antiarrhythmic drugs.

Europace · 2024 · PMC11481279 · PMID 39412366

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While propranolol and bisoprolol had no clear effect on ORF 3a-mediated currents, application of metoprolol and carvedilol resulted in a trend towards inhibition of ORF 3a currents that did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.