Barely Significant
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Endothelial PHD2 deficiency induces apoptosis resistance and inflammation via AKT activation and AIP1 loss independent of HIF2α.

Am J Physiol Lung Cell Mol Physiol · 2024 · PMC11482463 · PMID 39159362

Europe PMCDOI
1
hedged sentence
0.0850
closest p · 1.7× alpha
0.0850
boldest claim

The sentences

showed a trendP = 0.085so close (0.05 < p ≤ 0.1)
Moreover, LMVECs isolated from patients with APAH with congenital cardiac shunts, often accompanied by hypoxemia that suppresses endothelial PHD2 activity, showed a trend toward increased STAT1/3 activation compared with control LMVECs from FD subjects ( P = 0.085 for pSTAT1, P = 0.036 for the combined pSTAT1 and pSTAT3 effect; Fig. 5 E ).

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