Barely Significant
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Effect of local prolonged-release incisional doxycycline on surgical site infection prophylaxis in abdominal colorectal surgery: the SHIELD 1 randomized clinical trial.

Int J Surg · 2024 · PMC11486998 · PMID 38869970

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Although D-PLEX produced a numerical reduction in the incidence of the primary outcome events, it did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.